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Acute and Chronic Inflammation

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Inflammation

Inflammation is the body’s response to tissue injury. There are two types: acute and chronic. Acute inflammation involves vasodilation, vascular leakage, and leukocyte emigration. Chronic inflammation occurs when the acute phase cannot be resolved and involves infiltration of various cells.

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Acute and Chronic Inflammation PPT Summary

  1. Acute inflammation involves vasodilation, vascular leakage, and leukocyte emigration.
  2. Vascular leakage occurs through mechanisms such as histamines and cytokine mediators.
  3. Leukocytes leave the vasculature through a sequence of events including margination, rolling, adhesion, transmigration, and chemotaxis.
  4. Chronic inflammation is characterized by the infiltration of macrophages, lymphocytes, plasma cells, eosinophils, and mast cells.
  5. The systemic effects of inflammation include fever, anorexia, skeletal muscle protein degradation, hypotension, and leukocytosis.

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