Acute and Chronic Inflammation

Acute and Chronic Inflammation PPT Summary

1. Acute inflammation involves vasodilation, vascular leakage, and leukocyte emigration.
2. Vascular leakage occurs through mechanisms such as histamines and cytokine mediators.
3. Leukocytes leave the vasculature through a sequence of events including margination, rolling, adhesion, transmigration, and chemotaxis.
4. Chronic inflammation is characterized by the infiltration of macrophages, lymphocytes, plasma cells, eosinophils, and mast cells.
5. The systemic effects of inflammation include fever, anorexia, skeletal muscle protein degradation, hypotension, and leukocytosis.

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