Ankylosing spondylitis (AS) is a seronegative inflammatory disease that mainly affects the axial skeleton, particularly the SI joint, and primarily impacts young males in their 3rd decade.
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| File Name | Ankylosing-Spondylitis.pptx |
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Ankylosing Spondylitis PPT Summary
- Ankylosing spondylitis primarily affects young males in their 3rd decade and is characterized by inflammation in the axial skeleton, particularly the SI joint.
- Genetic factors, such as the HLA B-27 gene, play a significant role in the susceptibility to developing AS.
- Clinical features of AS include extra-articular involvement, posture changes, and different phases of the disease.
- Diagnosis of AS is based on clinical symptoms and radiographic findings, with treatment options ranging from NSAIDs to anti-TNF-alpha drugs and surgical interventions.
- Surgical interventions, such as spine osteotomy and total hip replacement, may be necessary for managing deformities, fractures, and severe cases of AS.
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