
Multiple Endocrine Neoplasia (MEN) syndromes are genetic disorders affecting the endocrine system, resulting in various tumours and cancers. Classified into MEN1 and MEN2, these syndromes can involve multiple glands, including the parathyroid, pancreas, and pituitary.
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Men Syndromes PPT Summary
- MEN syndromes are inherited, with multiple endocrine glands potentially affected, leading to various cancers.
- MEN1 syndrome primarily involves mutations in the MEN1 gene, resulting in significant clinical manifestations, particularly parathyroid tumours.
- Early diagnosis and effective genetic screening for RET mutations are critical to ensure the management and timely intervention of MEN2 syndrome.
- The clinical presentations of these syndromes often vary considerably, with symptoms and severity influenced by the specific endocrine tissues involved.
- Surgical intervention and continued monitoring play an essential role in the management of endocrine tumours associated with MEN syndrome.
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