Rheumatic fever is a systemic disease that primarily affects children and follows a streptococcal infection. It is characterized by inflammation of connective tissue, particularly in the heart, blood vessels, joints, subcutaneous tissue, and CNS.
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Rheumatic Fever PPT Summary
- Rheumatic fever is a systemic disease that primarily affects children following a streptococcal infection.
- It is more common in children aged 5-15 years and in third-world countries with poor sanitation and overcrowding.
- The pathogenesis involves a delayed immune response and antibody-induced immunological damage.
- Clinical manifestations include migratory polyarthritis, pancarditis, Sydenham chorea, erythema marginatum, and subcutaneous nodules.
- Diagnosis is mainly clinical, based on the Modified Jones Criteria.
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